Main Outcomes and Measures Outcomes of interest included 5-, 9-, and 13-year dementia risk. The data were split into training and testing data sets to separately establish and validate a prediction model. Individual analyses of time end points were concluded at the first dementia diagnosis during the follow-up period. Data analysis was performed from June 7 to September 15, 2021. Objective To develop a point risk score prediction model of dementia.ĭesign, Setting, and Participants This study used a large UK population-based prospective cohort study conducted between March 13, 2006, and October 1, 2010. Identifying preclinical risk factors of dementia could help prevent or delay its progression. Importance Although researchers have devoted substantial efforts, money, and time to studying the causes of dementia and the means to prevent it, no effective treatment exists yet. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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